Guzmán Martínez-Valls P L, Ferrero Doria R, Morga Egea J P, Navas Pastor J, García Ligero J, Tomás Ros M, Rico Galiano J L, Sempere Gutiérrez A, Fontana Compiano L O
Servicio de Urología, Hospital General Universitario de Murcia.
Actas Urol Esp. 1998 Apr;22(4):343-9.
The infection caused by the Human Immunodeficiency Virus (HIV), a retrovirus, leads to a progressive decline and to the suppression of cell-mediated immunity favouring the development of opportunistic diseases and potentially fatal neoplasias which are practically innocuous in individuals with an intact immunologic system. The number of AIDS cases recorded in Spain until March 1997 was 45,132, with a revised mortality rate of 58%. Cases in Murcia total 713 up to October 1997, of which 217 patients are being monitored in the AIDS Unit in our centre, 414 individuals have died in the region. It is well know that about one third of patients with diagnosed AIDS or who are HIV carriers will develop some type of genitourinary lesion, either as a result of a renal disorder, concurrent or not with HIV, or any other condition directly related to the infection. This is a report on our Service's experience in the treatment of HIV patients with genitourinary symptoms that, in a total of 15 cases, required our intervention. Emphasis is placed on the incidence of nephrolithiasis secondary to therapy with protease inhibitors over the last few months following introduction of this new therapeutic tool, prostatitis due to salmonella, and inlaid cystitis among others.
人类免疫缺陷病毒（HIV）是一种逆转录病毒，由其引起的感染会导致细胞介导免疫功能逐渐衰退并受到抑制，从而引发机会性疾病和潜在致命性肿瘤，而这些疾病在免疫系统健全的个体中实际上是无害的。截至1997年3月，西班牙记录的艾滋病病例数为45,132例，修订后的死亡率为58%。截至1997年10月，穆尔西亚的病例总数为713例，其中217名患者在我们中心的艾滋病科室接受监测，该地区已有414人死亡。众所周知，约三分之一被诊断为艾滋病或HIV携带者的患者会出现某种类型的泌尿生殖系统病变，这要么是由肾脏疾病导致的，无论是否与HIV并发，要么是由与感染直接相关的任何其他病症引起的。这是一份关于我们科室治疗有泌尿生殖系统症状的HIV患者经验的报告，共有15例患者需要我们进行干预。重点关注在引入这种新治疗手段后的过去几个月里，蛋白酶抑制剂治疗继发的肾结石发病率、沙门氏菌引起的前列腺炎以及镶嵌性膀胱炎等情况。
