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七氟醚或氟烷用于小儿气管插管的麻醉诱导时间。

Anaesthetic induction time for tracheal intubation using sevoflurane or halothane in children.

作者信息

Inomata S, Yamashita S, Toyooka H, Yaguchi Y, Taguchi M, Sato S

机构信息

Department of Anaesthesia, Institute of Clinical Medicine, University of Tsukuba, Ibaraki, Japan.

出版信息

Anaesthesia. 1998 May;53(5):440-5. doi: 10.1046/j.1365-2044.1998.00338.x.

Abstract

The current study was designed to determine the anaesthetic induction time required for tracheal intubation (TimeEI) with equipotent inspired concentrations of 5% sevoflurane and 2.5% halothane in oxygen. TimeEI that prevents 50% and 95% of patients from coughing and gross purposeful muscular movements after intubation was defined as TimeEI50 and TimeEI95, respectively. Thirty-six patients aged 1-7 years were enrolled in the study. Anaesthesia was induced via mask and when TimeEI attained a predetermined value, intubation was performed using an uncuffed tube. Each TimeEI at which tracheal intubation was attempted was predetermined according to the up-and-down method. When intubation was accomplished without gross purposeful muscular movements, it was considered a smooth intubation. Determination with this method revealed that TimeEI50 and TimeEI95 for the sevoflurane/halothane groups were 147/214 s and 194/255 s, respectively. In conclusion, it is possible to determine TimeEI using an inspired sevoflurane concentration of 5% and halothane 2.5% in oxygen. The technique with 5% sevoflurane seems more practical for paediatric anaesthesia induction in busy clinical situations.

摘要

本研究旨在确定在氧气中使用等效吸入浓度的5%七氟醚和2.5%氟烷进行气管插管所需的麻醉诱导时间(TimeEI)。将插管后能防止50%和95%的患者咳嗽及出现明显有意识肌肉运动的TimeEI分别定义为TimeEI50和TimeEI95。36名年龄在1至7岁的患者纳入本研究。通过面罩诱导麻醉,当TimeEI达到预定值时,使用无套囊导管进行插管。每次尝试气管插管的TimeEI均根据上下法预先确定。若插管过程中未出现明显有意识的肌肉运动,则视为插管顺利。用该方法测定发现,七氟醚/氟烷组的TimeEI50和TimeEI95分别为147/214秒和194/255秒。总之,使用氧气中5%的七氟醚吸入浓度和2.5%的氟烷可以确定TimeEI。在繁忙的临床情况下,5%七氟醚技术似乎更适用于小儿麻醉诱导。

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