Galloway J H, Ashford M, Marsh I D, Holden M, Forrest A R
Department of Clinical Chemistry, Royal Hallamshire Hospital, Sheffield, UK.
J Clin Pathol. 1998 Apr;51(4):326-9. doi: 10.1136/jcp.51.4.326.
A method is described for the confirmation/identification of a range of commonly misused drugs in urine samples. The method has been used for two years without problems for a range of purposes including hospital/clinic drugs of misuse screening and for toxicology in coroner's cases. Urine samples which have given a positive result on immunochemical screening for a particular drug group or groups (for example, opiates) can be processed with identification of the drugs present using a single procedure. Bond ElutCertify columns are used for the extraction of drugs from the samples followed by propionylation and gas chromatography with mass selective detection.
本文描述了一种用于确认/鉴定尿液样本中一系列常见滥用药物的方法。该方法已使用两年，用于包括医院/诊所药物滥用筛查以及验尸官案件毒理学等一系列目的，均未出现问题。对特定药物组（例如阿片类药物）免疫化学筛查呈阳性的尿液样本，可通过单一程序鉴定其中存在的药物。使用Bond ElutCertify柱从样本中提取药物，随后进行丙酰化和带质量选择性检测的气相色谱分析。
