Groch M W, Gottlieb S, Mallon S M, Miale A
J Nucl Med. 1976 Oct;17(10):930-6.
A mobile dual-probe system has been developed for the rapid bedside measurement of left ventricular ejection fraction (LVEF) from the beat-to-beat count rate variations that occur during the transit of a single radionuclide bolus through the left ventricle (LV). Cardiac output, pulmonary blood volume, and left ventricular end-diastolic volume can also be calculated. The dual-probe system incorporates a central collimated probe for monitoring activity in the LV surrounded by an annular detector collimated in such a manner as to provide simultaneous real-time monitoring of the LV background activity. The LVEFs obtained from this system correlated well with LVEFs derived from conventional single-plane contrast angiography (r=0.90) in a series of 33 patients with coronary artery disease. Positioning the dual probe over the midpoint of the LV is accomplished with standard M-mode ultrasound. Since the method is noninvasive and sensitive to volume changes in the LV, the dual probe is particularly useful for monitoring seriously ill patients as well as those with segmental wall-motion abnormalities.
已开发出一种移动式双探头系统,用于在床边快速测量左心室射血分数(LVEF),其依据的是单个放射性核素弹丸通过左心室(LV)期间逐搏计数率的变化。心输出量、肺血容量和左心室舒张末期容积也可计算得出。该双探头系统包括一个中央准直探头,用于监测左心室内的活性,其周围环绕着一个环形探测器,该探测器的准直方式可对左心室背景活性进行同步实时监测。在一系列33例冠心病患者中,通过该系统获得的左心室射血分数与传统单平面造影血管造影得出的左心室射血分数相关性良好(r = 0.90)。使用标准M型超声将双探头置于左心室中点上方。由于该方法是非侵入性的,且对左心室容积变化敏感,因此双探头对于监测重症患者以及有节段性室壁运动异常的患者特别有用。