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[慢性肾功能不全青少年患者的氮平衡]

[Nitrogen balance in adolescent patients with chronic renal insufficiency].

作者信息

Lama More R A, Alonso Melgar A, Navarro Torres M

机构信息

Servicio de Nefrología Pediátrica, Hospital Universitario Materno Infantil La Paz, Universidad Autónoma de Madrid, España.

出版信息

Nutr Hosp. 1998 May-Jun;13(3):138-43.

PMID:9662955
Abstract

UNLABELLED

Protein restriction in patients with chronic renal failure may be potentially beneficial, however the dangers in growing children of such restrictions must be considered. We analyzed the nitrogen balance in 60 chronic renal failure children (47 male y 13 female) Group A: 36 preadolescents. GFR was 54.5 +/- 25.6 ml/min/1.73 m2. Group B: 24 adolescents. GFR 52.7 +/- 25.4 ml/min/1.73 m2.

RESULTS

55% of patients had a negative balance. 72% preadolescents and 17% of adolescents had positive nitrogen balance A good correlation was found between the range of energy and protein intake and nitrogen balance.

CONCLUSIONS

  1. A good correlation was found between nitrogen balance and the range of energy and protein intake but no correlation with the renal function degree. 2. Adolescents had nitrogen balance negative. 3. It is necessary turn-over protein studies in this patients to know the requirements in children with chronic renal failure.
摘要

未标记

对慢性肾衰竭患者限制蛋白质摄入可能具有潜在益处,然而必须考虑对成长中儿童进行此类限制的危险性。我们分析了60例慢性肾衰竭儿童(47例男性和13例女性)的氮平衡。A组:36例青春期前儿童。肾小球滤过率为54.5±25.6毫升/分钟/1.73平方米。B组:24例青少年。肾小球滤过率52.7±25.4毫升/分钟/1.73平方米。

结果

55%的患者氮平衡为负。72%的青春期前儿童和17%的青少年氮平衡为正。能量和蛋白质摄入范围与氮平衡之间存在良好的相关性。

结论

  1. 氮平衡与能量和蛋白质摄入范围之间存在良好的相关性,但与肾功能程度无关。2. 青少年氮平衡为负。3. 有必要对这些患者进行蛋白质周转研究,以了解慢性肾衰竭儿童的需求。

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