Chieffi P P, Sens Y A, Paschoalotti M A, Miorin L A, Silva H G, Jabur P
Tropical Medicine Institute of São Paulo, Brazil.
Rev Soc Bras Med Trop. 1998 Jul-Aug;31(4):333-7. doi: 10.1590/s0037-86821998000400001.
The frequency of infection by Cryptosporidium parvum was determined in two groups of renal patients submitted to immunosuppression. One group consisted of 23 renal transplanted individuals, and the other consisted of 32 patients with chronic renal insufficiency, periodically submitted to hemodialysis. A third group of 27 patients with systemic arterial hypertension, not immunosuppressed, was used as control. During a period of 18 months all the patients were submitted to faecal examination to detect C. parvum oocysts, for a total of 1 to 6 tests per patient. The results showed frequencies of C. parvum infection of 34.8%, 25% and 17.4%, respectively, for the renal transplanted group, the patients submitted to hemodialysis and the control group. Statistical analysis showed no significant differences among the three groups even though the frequency of C. parvum infection was higher in the transplanted group. However, when the number of fecal samples containing C. parvum oocysts was taken in account, a significantly higher frequency was found in the renal transplanted group.
在两组接受免疫抑制的肾病患者中测定了微小隐孢子虫的感染频率。一组由23名肾移植个体组成,另一组由32名慢性肾功能不全患者组成,这些患者定期接受血液透析。第三组27名未接受免疫抑制的系统性动脉高血压患者作为对照。在18个月的时间里,所有患者都接受了粪便检查以检测微小隐孢子虫卵囊,每位患者总共进行1至6次检测。结果显示,肾移植组、接受血液透析的患者组和对照组的微小隐孢子虫感染频率分别为34.8%、25%和17.4%。统计分析表明,尽管移植组的微小隐孢子虫感染频率较高,但三组之间无显著差异。然而,当考虑到含有微小隐孢子虫卵囊的粪便样本数量时,肾移植组的频率明显更高。