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视网膜母细胞瘤患者的多孔聚乙烯眼眶植入物

Porous polyethylene orbital implant in patients with retinoblastoma.

作者信息

Karcioglu Z A, al-Mesfer S A, Mullaney P B

机构信息

King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.

出版信息

Ophthalmology. 1998 Jul;105(7):1311-6. doi: 10.1016/S0161-6420(98)97040-3.

Abstract

OBJECTIVE

The purpose of the study was to assess integration of porous polyethylene allografts in 37 anophthalmic sockets of retinoblastoma enucleations.

DESIGN

A clinical review.

PARTICIPANTS

Thirty-four patients (19 female, 15 male) whose age when diagnosed with retinoblastoma ranged from 1 to 72 months participated. Sixteen patients had unilateral retinoblastoma and 18 had bilateral retinoblastoma.

INTERVENTION

Enucleation (3 bilateral, 31 unilateral) with implantation of a porous polyethylene (PP) sphere (16-20 mm in diameter) was performed. Of the 37 spheres, 34 were primary implants and 3 were secondary implants. In the eight patients with postimplantation exposure, the PP implant had to be removed.

MAIN OUTCOME MEASURES

Data on eight sockets with exposed PP implant were measured.

RESULTS

There were no implant extrusions, but conjunctival dehiscence-exposure occurred in eight patients (21.6%). In 3 of 37 sockets, the volume replacement was not good, and in 5 cases, fornices were too shallow to accommodate a well-fitting prosthesis. In all but one socket, the overall cosmesis was graded subjectively from acceptable (grade 2) to excellent (grade 3).

CONCLUSIONS

Although the PP implant is a useful and a less-expensive alternative to hydroxyapatite in the porous matrix implant category, if conjunctival exposure takes place, the implant presents a serious management problem because of its nonresponsiveness to medical and surgical treatments.

摘要

目的

本研究旨在评估多孔聚乙烯同种异体移植物在37例视网膜母细胞瘤眼球摘除术后无眼球眼眶中的整合情况。

设计

临床回顾性研究。

参与者

34例患者(19例女性,15例男性)参与研究,其诊断为视网膜母细胞瘤时的年龄在1至72个月之间。16例患者为单侧视网膜母细胞瘤,18例为双侧视网膜母细胞瘤。

干预措施

进行眼球摘除术(3例双侧,31例单侧),并植入直径为16 - 20毫米的多孔聚乙烯(PP)球。37个球中,34个为初次植入,3个为二次植入。在8例植入后出现暴露的患者中,PP植入物不得不被移除。

主要观察指标

测量8例PP植入物暴露眼眶的数据。

结果

没有植入物挤出,但8例患者(21.6%)出现结膜裂开 - 暴露。在37个眼眶中的3个,容积替代效果不佳,5例中穹窿过浅,无法容纳合适的义眼。除1个眼眶外,所有眼眶的整体美容效果主观评分为可接受(2级)至优秀(3级)。

结论

尽管PP植入物在多孔基质植入物类别中是一种有用且成本较低的替代羟基磷灰石的材料,但如果发生结膜暴露,由于其对药物和手术治疗无反应,该植入物会带来严重的处理问题。

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