Chen M K, Wen Y S, Chang C C, Huang M T, Hsiao H C
Department of Otorhinolaryngology, Head and Neck Surgery, Chianghua Christian Hospital, Taiwan.
J Otolaryngol. 1998 Jun;27(3):141-4.
In the era of antibiotics, most deep neck infections can be cured by conservative treatment, but some still result in life-threatening complications. In this study, we discuss whether or not there are predisposing factors of complicated deep neck infection.
A retrospective chart review of patients presenting between 1988 and 1996 was conducted.
Among 214 deep neck infection patients, 18 cases resulted in lethal complications. We used the "dummy" variable with logistic regression as the statistical analysis method.
Patients with an underlying disease, neck swelling, and delay time had a positive correlation that was statistically significance (p < .05). Patients who were older, male, with complete blood count/differential count-positive finding and fever had positive correlation, but this was not statistically significant (p > .05).
Although complicated deep neck infection is a rapidly progressive disease with a high mortality, we can not thoroughly predict the prognosis or avoid it happening completely. But, if we can detect and pay more attention to the high-risk group of patients with use of aggressive therapy, the incidence of complicated deep neck infection may be reduced.
在抗生素时代，大多数颈部深部感染可通过保守治疗治愈，但仍有一些会导致危及生命的并发症。在本研究中，我们探讨颈部深部感染并发是否存在易感因素。
对1988年至1996年间就诊的患者进行回顾性病历审查。
在214例颈部深部感染患者中，18例出现致命并发症。我们使用带有逻辑回归的“虚拟”变量作为统计分析方法。
患有基础疾病、颈部肿胀和延迟时间的患者呈正相关，具有统计学意义（p <.05）。年龄较大、男性、全血细胞计数/分类计数呈阳性且发热的患者呈正相关，但无统计学意义（p>.05）。
尽管颈部深部感染并发是一种进展迅速、死亡率高的疾病，但我们无法完全预测其预后或避免其发生。但是，如果我们能够通过积极治疗检测并更多地关注高危患者群体，颈部深部感染并发的发生率可能会降低。
