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经颅磁刺激显示的知觉学习中的皮质可塑性。

Cortical plasticity in perceptual learning demonstrated by transcranial magnetic stimulation.

作者信息

Walsh V, Ashbridge E, Cowey A

机构信息

Department of Experimental Psychology, University of Oxford, UK.

出版信息

Neuropsychologia. 1998 Apr;36(4):363-7. doi: 10.1016/s0028-3932(97)00113-9.

DOI:10.1016/s0028-3932(97)00113-9
PMID:9665647
Abstract

Performance on a wide range of perceptual tasks improves with practice. Most accounts of perceptual learning are concerned with changes in neuronal sensitivity or changes in the way a stimulus is represented. Another possibility is that different areas of the brain are involved in performing a task while learning it and after learning it. Here we demonstrate that the right parietal cortex is involved in novel but not learned visual conjunction search. We observed that single pulse transcranial magnetic stimulation (TMS) to the right parietal cortex impairs visual conjunction search when the stimuli are novel and require a serial search strategy, but not once the particular search task has been learned. The effect of TMS returns when a different, novel, serial search task is presented.

摘要

通过练习,在各种感知任务上的表现会得到提高。大多数关于感知学习的解释都涉及神经元敏感性的变化或刺激表征方式的变化。另一种可能性是,大脑的不同区域在学习任务和学会任务后参与执行该任务。在这里,我们证明右侧顶叶皮层参与新颖的但非已学会的视觉联合搜索。我们观察到,当刺激是新颖的且需要串行搜索策略时,对右侧顶叶皮层进行单脉冲经颅磁刺激(TMS)会损害视觉联合搜索,但一旦学会了特定的搜索任务,就不会有这种损害。当呈现不同的、新颖的串行搜索任务时,TMS的效果又会出现。

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