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II类内含子结构元件的结构组织与机制功能

The architectural organization and mechanistic function of group II intron structural elements.

作者信息

Qin P Z, Pyle A M

机构信息

Howard Hughes Medical Institute, Department of Applied Physics, New York, NY 10032, USA.

出版信息

Curr Opin Struct Biol. 1998 Jun;8(3):301-8. doi: 10.1016/s0959-440x(98)80062-6.

Abstract

Group II introns are large, self-splicing RNAs and mobile genetic elements that provide good model systems for studies of RNA folding. The structures and mechanistic functions of individual domains are being elucidated, and long-range tertiary interactions between the domains are being identified, thus helping to define the three-dimensional architecture of the intron.

摘要

II类内含子是大型的自我剪接RNA和可移动遗传元件,为RNA折叠研究提供了良好的模型系统。各个结构域的结构和机制功能正在被阐明,并且结构域之间的长程三级相互作用也正在被识别,从而有助于确定内含子的三维结构。

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