Qin P Z, Pyle A M
Howard Hughes Medical Institute, Department of Applied Physics, New York, NY 10032, USA.
Curr Opin Struct Biol. 1998 Jun;8(3):301-8. doi: 10.1016/s0959-440x(98)80062-6.
Group II introns are large, self-splicing RNAs and mobile genetic elements that provide good model systems for studies of RNA folding. The structures and mechanistic functions of individual domains are being elucidated, and long-range tertiary interactions between the domains are being identified, thus helping to define the three-dimensional architecture of the intron.
II类内含子是大型的自我剪接RNA和可移动遗传元件，为RNA折叠研究提供了良好的模型系统。各个结构域的结构和机制功能正在被阐明，并且结构域之间的长程三级相互作用也正在被识别，从而有助于确定内含子的三维结构。
