Küster B, Mann M
Center for Experimental BioInformatics, Odense University, Denmark.
Curr Opin Struct Biol. 1998 Jun;8(3):393-400. doi: 10.1016/s0959-440x(98)80075-4.
Major recent advances in hardware performance, sample-handling procedures and software algorithms now allow reliable and sensitive mass spectrometric identification of proteins. Mass spectrometry vastly outperforms traditional sequencing technologies and thereby greatly facilitates the elucidation of the functions of individual proteins as well as multiprotein complexes and larger protein assemblages.
近年来,硬件性能、样品处理程序和软件算法取得了重大进展,现在能够对蛋白质进行可靠且灵敏的质谱鉴定。质谱分析大大优于传统测序技术,从而极大地促进了对单个蛋白质以及多蛋白复合物和更大蛋白质组合功能的阐明。