van Houten M A, Laseur M, Kimpen J L
Beatrix Children's Hospital, University Hospital Groningen, The Netherlands.
Eur J Pediatr. 1998 Jun;157(6):479-81. doi: 10.1007/s004310050858.
In paediatrics, antibiotics are among the most commonly prescribed drugs. Because of an overall rise in health care costs, lack of uniformity in drug prescribing and the emergence of antibiotic resistance, monitoring and control of antibiotic use is of growing concern and strict antibiotic policies are warranted. Before such a policy can be implemented, detailed knowledge of antibiotic prescribing patterns and related costs is important. In this study a shift of antibiotic prescription patterns over time is described in relation to hospital antibiotic expenditure.
A considerable shift in prescription patterns towards more expensive and broader spectrum antibiotics occurs in paediatrics, carrying a risk for the development of antibiotic resistance among the most prevalent micro-organisms in this age group.
在儿科,抗生素是最常开具的药物之一。由于医疗保健成本总体上升、药物处方缺乏一致性以及抗生素耐药性的出现,抗生素使用的监测和控制日益受到关注,严格的抗生素政策是必要的。在实施这样一项政策之前,详细了解抗生素处方模式和相关成本很重要。在本研究中,描述了抗生素处方模式随时间的变化及其与医院抗生素支出的关系。
儿科的处方模式发生了相当大的转变,转向使用更昂贵、更广谱的抗生素,这给该年龄组最常见微生物中抗生素耐药性的发展带来了风险。