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酸相关性食管狭窄的管理。

Management of acid-peptic esophageal strictures.

作者信息

Toledo-Pereyra L H, Michel H, Manifacio G, Humphrey E W

出版信息

J Thorac Cardiovasc Surg. 1976 Oct;72(4):518-24.

PMID:966784
Abstract

Eighty-nine patients with benign acid-peptic strictures of the esophagus were evaluated. Of these, 56 patients were treated by dilatation and medical therapy, whereas 33 underwent operative therapy because medical therapy failed. Three patients, all psychotic and having post-emetic strictures, required resection of the stricture and a colon interposition. Twenty-nine patients underwent a Belsey or Nissen fundoplication combined with esophageal dilatation. Fourteen of 29 had an associated vagotomy and 15 did not. Two patients of this 29 had a poor result, one of whom had a post-emetic stricture. Although the patients having a concurrent vagotomy and pyloroplasty had the more severe disease,there was no significant difference between the results in the two groups. It is concluded that most patients with such esophageal strictures may be adequately treated without resecting the stricture and that the routine addition of a vagotomy and drainage procedure is probably not indicated.

摘要

对89例食管良性酸蚀性狭窄患者进行了评估。其中,56例患者接受了扩张和药物治疗,而33例因药物治疗失败而接受了手术治疗。3例患者均为精神病患者且有呕吐后狭窄,需要切除狭窄段并进行结肠间置术。29例患者接受了贝尔西或尼森胃底折叠术联合食管扩张术。29例中有14例同时进行了迷走神经切断术,15例未进行。这29例中有2例效果不佳,其中1例有呕吐后狭窄。虽然同时进行迷走神经切断术和幽门成形术的患者病情更严重,但两组结果之间没有显著差异。得出的结论是,大多数此类食管狭窄患者无需切除狭窄段即可得到充分治疗,常规加用迷走神经切断术和引流手术可能并无必要。

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