Ohno-Machado L, Gennari J H, Murphy S N, Jain N L, Tu S W, Oliver D E, Pattison-Gordon E, Greenes R A, Shortliffe E H, Barnett G O
Decision Systems Group, Brigham and Women's Hospital, Boston, MA 02115, USA.
J Am Med Inform Assoc. 1998 Jul-Aug;5(4):357-72. doi: 10.1136/jamia.1998.0050357.
To allow exchange of clinical practice guidelines among institutions and computer-based applications.
The GuideLine Interchange Format (GLIF) specification consists of GLIF model and the GLIF syntax. The GLIF model is an object-oriented representation that consists of a set of classes for guideline entities, attributes for those classes, and data types for the attribute values. The GLIF syntax specifies the format of the test file that contains the encoding.
Researchers from the InterMed Collaboratory at Columbia University, Harvard University (Brigham and Women's Hospital and Massachusetts General Hospital), and Stanford University analyzed four existing guideline systems to derive a set of requirements for guideline representation. The GLIF specification is a consensus representation developed through a brainstorming process. Four clinical guidelines were encoded in GLIF to assess its expressivity and to study the variability that occurs when two people from different sites encode the same guideline.
The encoders reported that GLIF was adequately expressive. A comparison of the encodings revealed substantial variability.
GLIF was sufficient to model the guidelines for the four conditions that were examined. GLIF needs improvement in standard representation of medical concepts, criterion logic, temporal information, and uncertainty.
实现机构间及基于计算机的应用程序之间临床实践指南的交换。
指南交换格式（GLIF）规范由GLIF模型和GLIF语法组成。GLIF模型是一种面向对象的表示形式，由一组用于指南实体的类、这些类的属性以及属性值的数据类型组成。GLIF语法指定了包含编码的测试文件的格式。
来自哥伦比亚大学、哈佛大学（布莱根妇女医院和麻省总医院）以及斯坦福大学的InterMed协作实验室的研究人员分析了四个现有的指南系统，以得出一组指南表示的要求。GLIF规范是通过头脑风暴过程开发的一种共识表示形式。四个临床指南用GLIF进行编码，以评估其表达能力，并研究来自不同地点的两个人对同一指南进行编码时出现的变异性。
编码人员报告称GLIF具有足够的表达能力。编码比较显示出很大的变异性。
GLIF足以对所检查的四种情况的指南进行建模。GLIF在医学概念的标准表示、标准逻辑、时间信息和不确定性方面需要改进。
