Ikizler A A, Demirbas A, Johansson C B, Celik C, Serdar M, Yuksek H
Department of Chemistry, Karadeniz Technical University, Trabzon, Turkey.
Acta Pol Pharm. 1998 Mar-Apr;55(2):117-23.
Nine new 1,3,4-trisubstituted-4,5-dihydro-1H-1,2,4-triazol-5-ones were synthesized and characterized by elemental analysis, 1H NMR, IR and UV spectra. These new and 30 recently reported 3,4-disubstituted- and 1,3,4-trisubstituted-4,5-dihydro-1H-1,3,4-triazol-5-ones were screened for antibacterial, antitumor and anti-HIV activities.
合成了9种新的1,3,4-三取代-4,5-二氢-1H-1,2,4-三唑-5-酮，并通过元素分析、1H NMR、IR和UV光谱对其进行了表征。对这些新化合物以及最近报道的30种3,4-二取代和1,3,4-三取代-4,5-二氢-1H-1,3,4-三唑-5-酮进行了抗菌、抗肿瘤和抗HIV活性筛选。
