• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

某些4,5-二氢-1H-1,2,4-三唑-5-酮的合成及其抗菌活性

Synthesis and antibacterial activities of some 4,5-dihydro-1H-1,2,4-triazol-5-ones.

作者信息

Yüksek H, Demirbaş A, Ikizler A, Johansson C B, Celik C, Ikizler A A

机构信息

Department of Chemistry, Karadeniz Technical University, Trabzon, Turkey.

出版信息

Arzneimittelforschung. 1997 Apr;47(4):405-9.

PMID:9150862
Abstract

Twenty-one new 1-methyl- and 1-ethyl-3,4-disubstituted-4,5-dihydro- 1H-1,2,4-triazol-5-ones were synthesized and characterised by elemental analysis, 1H-NMR and IR spectra. These new and 16 recently reported derivatives of 4,5-dihydro-1H-1,2,4-triazol-5-one ring were screened for their antibacterial activities.

摘要

合成了21种新的1-甲基和1-乙基-3,4-二取代-4,5-二氢-1H-1,2,4-三唑-5-酮，并通过元素分析、1H-NMR和IR光谱对其进行了表征。对这些新的以及最近报道的16种4,5-二氢-1H-1,2,4-三唑-5-酮环衍生物进行了抗菌活性筛选。

相似文献

1
Synthesis and antibacterial activities of some 4,5-dihydro-1H-1,2,4-triazol-5-ones.某些4,5-二氢-1H-1,2,4-三唑-5-酮的合成及其抗菌活性
Arzneimittelforschung. 1997 Apr;47(4):405-9.
2
Synthesis and antitumor activities of some 4,5-dihydro-1H-1,2,4-triazol-5-ones.某些4,5-二氢-1H-1,2,4-三唑-5-酮的合成及其抗肿瘤活性
Acta Pol Pharm. 1997 Sep-Oct;54(5):363-70.
3
Synthesis and biological activities of some 4,5-dihydro-1H-1,2,4-triazol-5-one derivatives.某些4,5-二氢-1H-1,2,4-三唑-5-酮衍生物的合成及生物活性
Acta Pol Pharm. 1998 Mar-Apr;55(2):117-23.
4
Synthesis and biological evaluation of some novel triazol-3-ones as antimicrobial agents.合成及某些新型三唑-3-酮类化合物的生物评价作为抗菌剂。
Bioorg Med Chem Lett. 2011 Nov 1;21(21):6559-62. doi: 10.1016/j.bmcl.2011.08.049. Epub 2011 Aug 19.
5
Synthesis, antibacterial and antifungal activities of novel 1,2,4-triazolium derivatives.新型1,2,4 - 三唑鎓衍生物的合成、抗菌及抗真菌活性
Arch Pharm (Weinheim). 2009 Jul;342(7):386-93. doi: 10.1002/ardp.200800221.
6
Synthesis of some new 1,3,4-thiadiazol-2-ylmethyl-1,2,4-triazole derivatives and investigation of their antimicrobial activities.一些新型1,3,4-噻二唑-2-基甲基-1,2,4-三唑衍生物的合成及其抗菌活性研究
Eur J Med Chem. 2009 Jul;44(7):2896-903. doi: 10.1016/j.ejmech.2008.12.005. Epub 2008 Dec 16.
7
Synthesis of new S-derivatives of clubbed triazolyl thiazole as anti-Mycobacterium tuberculosis agents.作为抗结核分枝杆菌药物的棍状三唑基噻唑新S-衍生物的合成。
Bioorg Med Chem. 2007 Jun 15;15(12):3997-4008. doi: 10.1016/j.bmc.2007.04.003. Epub 2007 Apr 6.
8
Synthesis of novel sulfanilamide-derived 1,2,3-triazoles and their evaluation for antibacterial and antifungal activities.新型磺胺类 1,2,3-三唑的合成及其抗菌和抗真菌活性评价。
Eur J Med Chem. 2010 Oct;45(10):4631-9. doi: 10.1016/j.ejmech.2010.07.031. Epub 2010 Jul 24.
9
N-(chroman-4-ylidene)aryloxyacetohydrazones: synthesis and antimicrobial activity.N-（苯并二氢吡喃-4-亚基）芳氧基乙酰腙：合成与抗菌活性
Farmaco. 1997 Oct;52(10):631-3.
10
Synthesis and biological activities of some new 4,5-dihydro-1H-1,2,4-triazol-5-ones.一些新型4,5-二氢-1H-1,2,4-三唑-5-酮的合成及其生物活性
Acta Pol Pharm. 1996 Mar-Apr;53(2):117-21.

引用本文的文献

1
Synthesis and RP HPLC studies of biologically active semicarbazides and their cyclic analogues 1,2,4-triazol-3-ones.生物活性氨基脲及其环状类似物1,2,4 - 三唑 - 3 - 酮的合成与反相高效液相色谱研究
Monatsh Chem. 2012;143(4):657-667. doi: 10.1007/s00706-011-0715-z. Epub 2012 Jan 28.
2
Preparation, GIAO NMR calculations and acidic properties of some novel 4,5-dihydro-1H-1,2,4-triazol-5-one derivatives with their antioxidant activities.一些新型4,5-二氢-1H-1,2,4-三唑-5-酮衍生物的制备、GIAO NMR计算、酸性性质及其抗氧化活性
Int J Mol Sci. 2008 Jan;9(1):12-32. doi: 10.3390/ijms9010012. Epub 2008 Jan 8.
3
Synthesis, acidity and antioxidant properties of some novel 3,4-disubstituted-4,5-dihydro-1H-1,2,4-triazol-5-one derivatives.
一些新型3,4-二取代-4,5-二氢-1H-1,2,4-三唑-5-酮衍生物的合成、酸度及抗氧化性能
Molecules. 2008 Jan 19;13(1):107-21. doi: 10.3390/molecules13010107.
4
Synthesis and determination of pKa values of some new 3,4-disubstituted-4,5-dihydro-1H-1,2,4-triazol-5-one derivatives in non-aqueous solvents.一些新型3,4-二取代-4,5-二氢-1H-1,2,4-三唑-5-酮衍生物在非水溶剂中的合成及pKa值的测定
Molecules. 2004 Mar 31;9(4):232-40. doi: 10.3390/90400232.
5
Synthesis and non-aqueous medium titrations of some new 4-benzylidenamino-4,5-dihydro-1H-1,2,4-triazol-5-one derivatives.一些新型4-苄叉氨基-4,5-二氢-1H-1,2,4-三唑-5-酮衍生物的合成及非水介质滴定
Molecules. 2005 Aug 31;10(8):961-70. doi: 10.3390/10080961.
6
Synthesis of 4-amino-4,5-dihydro-1H-1,2,4-triazole-5-ones and their isatin-3-imine derivatives.4-氨基-4,5-二氢-1H-1,2,4-三唑-5-酮及其异吲哚酮-3-亚胺衍生物的合成
Molecules. 2005 Feb 28;10(2):376-82. doi: 10.3390/10020376.
7
A study on 4-acylamino-4,5-dihydro-1H-1,2,4-triazol-5-ones.关于4-酰氨基-4,5-二氢-1H-1,2,4-三唑-5-酮的一项研究。
Molecules. 2007 Aug 13;12(8):1805-16. doi: 10.3390/12081805.