Ferrara A, Numeroso R, Parola A, Fumagalli G
Minerva Med. 1976 Sep 22;67(44):2883-93.
Partial respiratory gas tension and acid-base equilibrium patterns were examined in polyglobulic patients subjected to acute blood depletion. The increase in oxyhaemoglobin concentration and fall in haematocrit value already described were confirmed. It was also noted that: 1) pH increased significantly in all subjects; 2) urinary osmolarity increased in all subjects; 3) blood sodium and potassium concentration increased significantly in 14 patients (1st group), but fell in the 2nd group (8 subjects). It is suggested, therefore, that acute blood depletion changes renal reabsorption of the main electrolytes, i.e. increased values in cases where a fall in glomerular arteriolar pressure leads to increased renal medullary osmolarity, and decreased values where a fall in circulation leads to increased arteriolar pressure, hyperosmolarity of the medulla, and retainment of liquids as opposed to electrolytes.
对患有红细胞增多症且经历急性失血的患者的部分呼吸气体张力和酸碱平衡模式进行了检查。已证实先前所述的氧合血红蛋白浓度增加和血细胞比容值下降。还注意到：1）所有受试者的pH值显著升高；2）所有受试者的尿渗透压升高；3）14例患者（第一组）的血钠和血钾浓度显著升高，但第二组（8例受试者）则下降。因此，有人认为急性失血会改变肾脏对主要电解质的重吸收，即当肾小球小动脉压力下降导致肾髓质渗透压升高时，重吸收值增加；而当循环血量下降导致小动脉压力升高、髓质高渗以及液体相对于电解质潴留时，重吸收值下降。
