Ekstrand J, Björkman L, Liu Y, Sköldqvist B, Björkner B
Avdelningen för odontologisk toxikologi, odontologiska fakulteten, Karolinska institutet, Huddinge sjukhus.
Lakartidningen. 1998 Jun 17;95(25):2946-9.
The acrylic content of modern dental materials poses a risk of adverse reactions. Although the quantities of the substances released are normally too small to cause systemic reactions, local reactions may occur resulting in damage to the skin. A study, in which 81 dental workers referred to dermatologists for a variety of adverse reactions were patch tested, showed work-related dermatoses to represent a serious problem for dental staff, sometimes entailing occupational disability and re-schooling. Much of this could be avoided by observing special precautions to prevent direct contact with the sensitising substances in composite materials used in dental surgery. Since the use of dental amalgam has been reduced to about 10 per cent of all fillings in Sweden, the prevalence of adverse local reactions to the acrylic composite materials which are used instead may be expected to increase.
现代牙科材料中的丙烯酸成分存在不良反应风险。尽管释放的物质数量通常过少，不会引起全身反应，但可能会发生局部反应，导致皮肤损伤。一项研究对81名因各种不良反应转诊至皮肤科医生处的牙科工作人员进行了斑贴试验，结果表明与工作相关的皮肤病对牙科工作人员来说是一个严重问题，有时会导致职业残疾和重新培训。通过采取特殊预防措施，避免直接接触牙科手术中使用的复合材料中的致敏物质，很大一部分问题是可以避免的。由于瑞典牙科汞合金的使用已降至所有补牙材料的约10%，预计取而代之使用的丙烯酸复合材料引起局部不良反应的发生率可能会上升。
