Tanawattanacharoen S, Suwajanakorn S, Uerpairojkit B, Wisawasukmongchol W, Boonkasemsanti W, Virutamasen P
Department of Obstetrics and Gynaecology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
J Med Assoc Thai. 1998 Jul;81(7):520-6.
Fifteen infertile women who required tubal passage evaluation by chromolaparoscopy were recruited. Those who had lower genital tract infection or abnormal uterine bleeding were excluded from the study. Transvaginal HyCoSy was performed during the first half of the menstrual cycle at least 24 hours prior to chromolaparoscopy. The results from both transvaginal HyCoSy and chromolaparoscopy were compared in assessing tubal patency and uterine pathology. A high correlation was noted regarding uterine examination using transvaginal HyCoSy compared with chromolaparoscopy (sensitivity, specificity, PPV and NPV were 91.7%, 33.3%, 84.6% and 50%, respectively). The correlation of the outcome between the two procedures in assessing tubal patency, when combining both tubes, was also high (sensitivity, specificity, PPV and NPV were 100%, 55.6%, 80% and 100%, respectively). The most common adverse event was only mild pelvic pain which did not necessitate any treatment. These preliminary results reveal the potential value of transvaginal HyCoSy as an alternative in infertility investigations. It seems to be as effective but less invasive than conventional chromolaparoscopy. The adverse events reported in this study relate more to the procedure (catheter insertion) rather than the trial substance.
招募了15名需要通过染色腹腔镜检查评估输卵管通畅性的不孕女性。患有下生殖道感染或子宫异常出血的女性被排除在研究之外。经阴道子宫输卵管超声造影（HyCoSy）在月经周期的前半期进行，至少在染色腹腔镜检查前24小时。比较经阴道HyCoSy和染色腹腔镜检查在评估输卵管通畅性和子宫病变方面的结果。与染色腹腔镜检查相比，经阴道HyCoSy在子宫检查方面具有高度相关性（敏感性、特异性、阳性预测值和阴性预测值分别为91.7%、33.3%、84.6%和50%）。在评估双侧输卵管通畅性时，两种检查方法结果的相关性也很高（敏感性、特异性、阳性预测值和阴性预测值分别为100%、55.6%、80%和100%）。最常见的不良事件只是轻度盆腔疼痛，无需任何治疗。这些初步结果揭示了经阴道HyCoSy作为不孕检查替代方法的潜在价值。它似乎与传统染色腹腔镜检查同样有效，但侵入性较小。本研究中报告的不良事件更多与操作（导管插入）有关，而非试验物质。
