将皮肤肉瘤实验性传播至加拿大梭鲈（Stizostedion canadense）。

Experimental transmission of dermal sarcoma to the sauger Stizostedion canadense.

作者信息

Holzschu D L, Wooster G A, Bowser P R

机构信息

Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, New York 14853, USA.

出版信息

Dis Aquat Organ. 1998 Feb 26;32(1):9-14. doi: 10.3354/dao032009.

DOI:10.3354/dao032009

PMID:9676258

Abstract

Walleye dermal sarcoma virus (WDSV) has been identified as the causative agent of a benign neoplasia of walleye Stizostedion vitreum, walleye dermal sarcoma (WDS). We conducted an experimental transmission regimen to determine if WDSV is capable of inducing dermal sarcoma in the closely related sauger S. canadense. Nearly all of young-of-the-year saugers (96%) inoculated with filtrates of spring-collected tumors developed dermal sarcomas, while all of the inoculated walleyes developed tumors. Most of the sauger tumors were limited to the skin, but invasive tumors, similar to those previously observed in experimental walleyes, were observed in some fish.

摘要

大眼狮鲈皮肤肉瘤病毒（WDSV）已被确认为大眼狮鲈（Stizostedion vitreum）良性肿瘤——大眼狮鲈皮肤肉瘤（WDS）的病原体。我们进行了一项实验性传播方案，以确定WDSV是否能够在亲缘关系密切的加拿大鲈（S. canadense）中诱发皮肤肉瘤。几乎所有接种春季采集肿瘤滤液的当年幼加拿大鲈（96%）都患上了皮肤肉瘤，而所有接种的大眼狮鲈都长出了肿瘤。大多数加拿大鲈的肿瘤局限于皮肤，但在一些鱼中观察到了侵袭性肿瘤，类似于之前在实验性大眼狮鲈中观察到的肿瘤。