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[黄斑中心凹下新生血管膜的手术治疗]

[Surgery of sub-foveal neovascular membranes].

作者信息

Gonvers M, Uffer S, Bovey E

机构信息

Clinique ophtalmologique universitaire, Lausanne.

出版信息

Klin Monbl Augenheilkd. 1998 May;212(5):334-8. doi: 10.1055/s-2008-1034899.

Abstract

BACKGROUND

To present the functional, angiographic and electron microscopic results of 3 patients who underwent surgical removal of a subfoveolar neovascularisation. These patients are representative of the most common indications for subfoveolar surgery.

MATERIAL AND METHOD

In one case, the neovascularization originated from an old chorioretinal scar close to the macula; in another case, it was associated with high myopia; in the last case the neovascularization was coupled with an age-related macular degeneration (ARMD). The 3 removal neovascular membranes were examined by electron microscopy. Indocyanine green and fluorescein angiographies were performed in all 3 cases before and after surgery.

RESULTS

Visual recovery was excellent in the case of neovasularization and old chorioretinitis scar; it was minimal in the case of high myopia; no objective improvement was found in the case of ARMD. Electron microscopic examination did not always allow to determine accurately if the neovascularization was located in the subretinal space or under the pigment epthelium.

CONCLUSIONS

These results match those already published: surgical prognosis is the best when neovascularization is in the subretinal space and when the pigment epithelium has not been damaged by the underlying disease or by the surgical maneuvers. Electron microscopic examination is not easy to interpret.

摘要

背景

介绍3例接受黄斑下新生血管膜手术切除患者的功能、血管造影及电子显微镜检查结果。这些患者代表了黄斑下手术最常见的适应证。

材料与方法

1例患者的新生血管起源于靠近黄斑的陈旧性脉络膜视网膜瘢痕;另1例与高度近视有关;最后1例新生血管与年龄相关性黄斑变性(ARMD)相关。对切除的3块新生血管膜进行电子显微镜检查。所有3例患者在手术前后均进行了吲哚菁绿和荧光素血管造影。

结果

新生血管合并陈旧性脉络膜视网膜炎瘢痕的患者视力恢复极佳;高度近视患者视力恢复极小;ARMD患者未发现客观改善。电子显微镜检查并不总能准确确定新生血管是位于视网膜下间隙还是色素上皮下。

结论

这些结果与已发表的结果相符:当新生血管位于视网膜下间隙且色素上皮未因潜在疾病或手术操作而受损时,手术预后最佳。电子显微镜检查结果不易解读。

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