Submolecular resolution of single macromolecules with atomic force microscopy.
作者信息
Czajkowsky D M, Shao Z
机构信息
Department of Molecular Physiology and Biological Physics, University of Virginia School of Medicine, Charlottesville 22908, USA.
出版信息
FEBS Lett. 1998 Jun 23;430(1-2):51-4. doi: 10.1016/s0014-5793(98)00461-x.
PMID:9678593
Abstract
The intrinsically high signal-to-noise ratio of atomic force microscopy (AFM) permits structural determination of individual macromolecules to, at times, subnanometer resolution directly from unprocessed images, avoiding the conditions and possible consequences of averaging over an ensemble of molecules. In this article, we will review some of the most recent achievements in imaging single macromolecules with AFM.
摘要
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