Pekarek R S, Evans G W
Proc Soc Exp Biol Med. 1976 Sep;152(4):573-5. doi: 10.3181/00379727-152-39443.
Leukocytic endogenous mediator (LEM) was shown to produce a significant increase in the intestinal absorption of zinc within 7 hr after its administration to normal rats. Consistent with earlier studies, LEM also produced a significant decrease in the plasma zinc concentration and an increased hepatic uptake of this metal which further demonstrates that LEM may be a key intermediate in altering zinc homeostasis during inflammation.
