Muir A
Department of Medicine, Ninewells Hospital and Medical School, Dundee.
Scott Med J. 1998 Jun;43(3):69-71. doi: 10.1177/003693309804300302.
The antiphospholipid syndrome is now well established as an important, acquired prothrombotic disorder. Advances are being made in the understanding of the condition and the paradox of the in vitro anticoagulation, and the in vivo prothrombotic tendency. Newer and better assays for the diagnosis of antiphospholipid syndrome can be expected in the near future. Large, multi-centre, controlled trials to determine the optimum treatment of patients who test positive for the antiphospholipid syndrome, but have not suffered a thrombotic event, are required.
抗磷脂综合征现已被确认为一种重要的获得性血栓前状态疾病。在对该病症以及体外抗凝与体内血栓前倾向这一矛盾现象的理解方面正取得进展。预计在不久的将来会有更新、更好的抗磷脂综合征诊断检测方法。需要开展大规模、多中心、对照试验,以确定抗磷脂综合征检测呈阳性但尚未发生血栓事件的患者的最佳治疗方案。