Kammerer M, Pinault L
Departement de Biologie et Pharmacologie, Ecole Nationale Veterinaire de Nantes, La Chantrerie, France.
Vet Hum Toxicol. 1998 Aug;40(4):197-9.
In animals, chronic exposure to nitrates has been shown to affect vitamin A nutrition, and researchers have explored this effect with conflicting results. To study this relationship, 24 female rabbits were given 8, 250 or 500 mg nitrate/L drinking water for 22 w, and their second litters were given the same dose for 5 w from 18 to 53 d of age. Liver samples were analyzed for retinol and retinyl palmitate. There was no effect of the nitrate on total liver vitamin A stores, but the balance between esterified and nonesterified forms of retinol was altered in pregnant females and their weaned young.
在动物实验中，已证实长期接触硝酸盐会影响维生素A的营养状况，研究人员对这一影响进行了探索，但结果相互矛盾。为了研究这种关系，给24只雌性兔子饮用硝酸盐含量为8、250或500毫克/升的水，持续22周，在其第二窝幼崽18至53日龄时，也给它们饮用相同剂量的水，持续5周。对肝脏样本进行视黄醇和棕榈酸视黄酯分析。硝酸盐对肝脏中维生素A的总储存量没有影响，但在怀孕母兔及其断奶幼崽中，视黄醇的酯化形式和非酯化形式之间的平衡发生了改变。
