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["由“切尔诺贝利”因素作用引发的脂质过氧化过程的趋势和强度"]

[The trends and intensity of lipid peroxidation processes initiated by the action of "Chernobyl" factors].

作者信息

Paranich A V, Karpenko N A, Alesina M Iu, Marishina T A

机构信息

Kharkov State University, Ukraine.

出版信息

Radiats Biol Radioecol. 1998 May-Jun;38(3):384-8.

PMID:9682731
Abstract

The 45-day's action of nutritional radionuclides (137Cs, 90Sr, 40K) by inside organism irradiation at doses: 0.16 sGy, 0.55 cGy, 5.5 cGy was investigated. The blood, muscles, heart, kidneys, lung, liver, brain, spleen and testis were studied. The content of dienes, trienes, oxodienes, tetraenes conjugates and malondialdehyde were researched. The level of dienes increased in blood and kidneys; MDA--in spleen than more, that more of dose irradiation. Content of oxodienes, trienes and tetraenes (the biological activity eicosanoids) decreased at kidneys, lung, brain and spleen. At total, these parameters by organism's adaptational systems controlled at physiological conditions.

摘要

研究了营养性放射性核素(137Cs、90Sr、40K)以0.16 sGy、0.55 cGy、5.5 cGy的剂量在体内照射45天的作用。对血液、肌肉、心脏、肾脏、肺、肝脏、大脑、脾脏和睾丸进行了研究。研究了二烯、三烯、氧代二烯、四烯共轭物和丙二醛的含量。血液和肾脏中二烯的含量增加;脾脏中丙二醛的含量增加得更多,且照射剂量越高增加得越多。肾脏、肺、大脑和脾脏中氧代二烯、三烯和四烯(具有生物活性的类二十烷酸)的含量降低。总体而言,这些参数在生理条件下由机体的适应系统控制。

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Radiats Biol Radioecol. 1998 May-Jun;38(3):384-8.
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