Koterov A N, Trebenok Z A, Pushkareva N B, Nikol'skiĭ A V
State Research Center of Russia, Institute of Biophysics, Moscow.
Radiats Biol Radioecol. 1998 May-Jun;38(3):432-7.
Zn-MT and less apo MT (4-100 mkg/ml) in vitro stimulated the [3H]-thymidine incorporation in mice bone marrow cells, but ZnCl2, its combination with cysteine and mixture (ZnCl2 + cystine + albumin) inhibited DNA synthesis. In protected with Zn-MT (1-4 mg/kg) 10-15 min before irradiation (6 Gy) mice on 9th day after influencing the increasing of DNA replicative synthesis level and nuclear cell number in bone marrow were observed.
锌-金属硫蛋白和较少的脱辅基金属硫蛋白（4-100微克/毫升）在体外刺激了小鼠骨髓细胞中[3H]-胸苷的掺入，但氯化锌、其与半胱氨酸的组合以及混合物（氯化锌+胱氨酸+白蛋白）抑制了DNA合成。在照射（6戈瑞）前10-15分钟用锌-金属硫蛋白（1-4毫克/千克）进行保护的小鼠，在处理后的第9天观察到骨髓中DNA复制合成水平和核细胞数量增加。
