Saito Y, Sakuragawa N, Sasaki M, Sugai K, Hashimoto T
Department of Child Neurology, National Center Hospital for Mental, Nervous and Muscular Disorders, National Center of Neurology and Psychiatry, Kodaira, Tokyo, Japan.
Pediatr Neurol. 1998 Jul;19(1):65-8. doi: 10.1016/s0887-8994(98)00016-2.
A case of alternating hemiplegia of childhood is reported. Tonic fits and generalized tonic-clonic seizures developed during her infancy. Frequent twitching and apneic seizures appeared at 16 years of age. Zonisamide transiently suppressed the tonic, twitching and apneic seizures, as well as the facial and neck dystonia. Cranial computed tomography and magnetic resonance imaging revealed progressive vermian atrophy. Cerebellar dysfunction may play a role in the clinical features of some patients with alternating hemiplegia of childhood.
报告了一例儿童交替性偏瘫病例。患儿婴儿期出现强直性发作和全身性强直阵挛发作。16岁时出现频繁抽搐和呼吸暂停发作。唑尼沙胺短暂抑制了强直性、抽搐性和呼吸暂停发作以及面部和颈部肌张力障碍。头颅计算机断层扫描和磁共振成像显示小脑蚓部进行性萎缩。小脑功能障碍可能在一些儿童交替性偏瘫患者的临床特征中起作用。
