通过向视网膜静脉注射组织型纤溶酶原激活剂治疗视网膜中央静脉阻塞。
Treatment of central retinal vein occlusion by injection of tissue plasminogen activator into a retinal vein.
作者信息
Weiss J N
出版信息
Am J Ophthalmol. 1998 Jul;126(1):142-4. doi: 10.1016/s0002-9394(98)00086-5.
PURPOSE
To report the injection of tissue plasminogen activator into a retinal vein to treat central retinal vein occlusion.
METHODS
An 81-year-old woman with visual loss of the right eye secondary to central retinal vein occlusion developed central retinal vein occlusion and visual loss in her left eye. Treatment of her left eye with topical ocular hypotensive medications, pentoxifylline, and laser chorioretinal anastomosis was without benefit. Thereafter, she underwent vitreoretinal surgery, including tissue plasminogen activator injection into a branch retinal vein of her left eye.
RESULTS
The patient reported subjective improvement in the vision of her left eye. Ophthalmoscopic and fluorescein angiographic improvement were also noted.
CONCLUSION
The feasibility of cannulating a retinal vein for treatment has been demonstrated.
目的
报告向视网膜静脉注射组织型纤溶酶原激活剂治疗视网膜中央静脉阻塞。
方法
一名81岁女性因右眼视网膜中央静脉阻塞导致视力丧失，随后左眼也出现视网膜中央静脉阻塞和视力丧失。使用局部降眼压药物、己酮可可碱和激光脉络膜视网膜吻合术治疗其左眼均无效果。此后，她接受了玻璃体视网膜手术，包括向左眼的一支视网膜静脉注射组织型纤溶酶原激活剂。
结果
患者报告左眼视力主观上有所改善。眼底镜检查和荧光素血管造影检查也显示有改善。
结论
已证明通过插管进入视网膜静脉进行治疗的可行性。
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