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用作抗糖尿病药物的植物的降血糖作用研究。

Study of the anti-hyperglycemic effect of plants used as antidiabetics.

作者信息

Alarcon-Aguilara F J, Roman-Ramos R, Perez-Gutierrez S, Aguilar-Contreras A, Contreras-Weber C C, Flores-Saenz J L

机构信息

Departamento de Ciencias de la Salud, Universidad Autónoma Metropolitana Iztapalapa, México, DF, México.

出版信息

J Ethnopharmacol. 1998 Jun;61(2):101-10. doi: 10.1016/s0378-8741(98)00020-8.

Abstract

The purpose of this research was to study the anti-hyperglycemic effect of 28 medicinal plants used in the treatment of diabetes mellitus. Each plant was processed in the traditional way and intragastrically administered to temporarily hyperglycemic rabbits. The results showed that eight out of the 28 studied plants significantly decrease the hyperglycemic peak and/or the area under the glucose tolerance curve. These plants were: Guazuma ulmifolia, Tournefortia hirsutissima, Lepechinia caulescens, Rhizophora mangle, Musa sapientum, Trigonella foenum graceum, Turnera diffusa, and Euphorbia prostrata. The results suggest the validity of their clinical use in diabetes mellitus control, after their toxicological investigation.

摘要

本研究的目的是研究用于治疗糖尿病的28种药用植物的降血糖作用。每种植物均采用传统方法加工,并对暂时性高血糖兔子进行胃内给药。结果显示,在研究的28种植物中,有8种能显著降低高血糖峰值和/或糖耐量曲线下面积。这些植物分别是:危地马拉破布木、多毛紫丹、茎生唇萼薄荷、红树、香蕉、胡芦巴、白花时钟花和铺散大戟。研究结果表明,在进行毒理学研究后,它们在控制糖尿病方面的临床应用是有效的。

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