Ghosh D, Sengupta J
Department of Physiology, All India Institute of Medical Sciences, New Delhi.
Hum Reprod Update. 1998 Mar-Apr;4(2):153-68. doi: 10.1093/humupd/4.2.153.
It is becoming increasingly evident that growth factors and cytokines play crucial roles in the process of blastocyst implantation. Endometrial differentiation and secretions, embryo development and secretions, and embryo-endometrium interaction leading to implantation require continuous and synchronous dialogue between these two compartments involving endocrine and paracrine regulators. In this review, a model of the endocrinology and paracrinology of blastocyst implantation in the primate is described.
越来越明显的是,生长因子和细胞因子在囊胚着床过程中起着至关重要的作用。子宫内膜的分化和分泌、胚胎的发育和分泌,以及导致着床的胚胎与子宫内膜的相互作用,需要这两个部分之间通过内分泌和旁分泌调节因子进行持续且同步的对话。在这篇综述中,描述了灵长类动物囊胚着床的内分泌学和旁分泌学模型。