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[锝-99m-锡胶体放射性核素扫描在评估骨科植入物感染中的应用]

[Radionuclide scan with TC-99m-tin colloid in the evaluation of orthopedic implant infections].

作者信息

Muñoz A, Ricart Y, Hernández Hermoso J, Roca M, Fernández A, García V, Mora J, Martín-Comín J

机构信息

Servicio de Medicina Nuclear. Hospital de Bellvitge. Feixa llarga s/n. 08907 Hospitalet de Llobregat.

出版信息

Rev Esp Med Nucl. 1998;17(3):152-7.

PMID:9683853
Abstract

We have studied 26 patients (32-77 years old, 16 females) with suspicion of joint arthroplasty infection: 11 total hip replacements, 12 total knee replacements and 3 osteosinthesys. A bone scintigraphy with MDP-99mTc, a scintigraphy with HMPAO-WBC and a scintigraphy with 99mTc-stannous colloid were made in all patients. The final diagnostic was based in joint cultures and clinic and radiologic evolution of the patients. The earliest phase of the bone scintigraphy was positive in 18 patients. The later phase was positive in all them. The WBC was positive in 20 out of 26 patients. The bone marrow scintigraphy showed a congruent pattern with WBC in 18 patients (17 infected and 1 without infection). The other ones (8 patients) showed an incongruent pattern (7 with infection and 1 without it). The results show that the bone marrow scintigraphy with 99mTc-stannous colloid improves the accuracy of the diagnostic of bone prosthesis infection and should be included into the diagnosis protocol of this disease.

摘要

我们研究了26例疑似关节置换感染的患者(年龄32 - 77岁,女性16例):11例全髋关节置换术,12例全膝关节置换术和3例骨固定术。所有患者均进行了99mTc - MDP骨闪烁显像、HMPAO - WBC闪烁显像和99mTc - 锡胶体闪烁显像。最终诊断基于关节培养以及患者的临床和影像学演变。骨闪烁显像的早期阶段在18例患者中呈阳性。后期阶段在所有患者中均呈阳性。26例患者中有20例WBC呈阳性。骨髓闪烁显像在18例患者中显示出与WBC一致的模式(17例感染,1例未感染)。其他患者(8例)显示出不一致的模式(7例感染,1例未感染)。结果表明,99mTc - 锡胶体骨髓闪烁显像提高了骨假体感染诊断的准确性,应纳入该疾病的诊断方案。

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