通过血清学和前病毒检测确定公牛中牛免疫缺陷样病毒的流行率。
Prevalence of bovine immunodeficiency-like virus in bulls as determined by serology and proviral detection.
作者信息
Jacobs R M, Jefferson B J, Suarez D L
机构信息
Department of Pathobiology, Ontario Veterinary College, University of Guelph, Ontario.
出版信息
Can J Vet Res. 1998 Jul;62(3):231-3.
We found the rate of bovine immunodeficiency-like virus (BIV) infection among bulls to be 9.6% using serology and 12.6% when tested by the polymerase chain reaction (PCR) for the presence of BIV provirus in peripheral blood leukocytes. Previously, we determined the frequency of BIV infection among the general dairy cow population in Ontario to be 5.5% based on serological analysis. Apparently, serological testing detects only 77% of BIV-infected bulls. Since almost a quarter of BIV-infected bulls may be seronegative, it is recommended that the PCR test be used to identify BIV-infected individuals. It is clear from the data presented here and supported by experimental studies that the latent carrier state is a relatively common outcome in ruminants infected with BIV.
我们发现，使用血清学检测公牛中牛免疫缺陷样病毒（BIV）感染率为9.6%，而通过聚合酶链反应（PCR）检测外周血白细胞中BIV前病毒时，感染率为12.6%。此前，我们基于血清学分析确定安大略省普通奶牛群体中BIV感染频率为5.5%。显然，血清学检测仅能检测出77%的BIV感染公牛。由于近四分之一感染BIV的公牛可能血清学呈阴性，因此建议使用PCR检测来识别感染BIV的个体。从这里呈现的数据以及实验研究可以清楚地看出，潜伏携带者状态在感染BIV的反刍动物中是相对常见的结果。
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