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拟南芥根中的细胞命运与细胞分化状态。

Cell fate and cell differentiation status in the Arabidopsis root.

作者信息

van den Berg C, Weisbeek P, Scheres B

机构信息

Department of Molecular Cell Biology, Utrecht University, The Netherlands.

出版信息

Planta. 1998 Aug;205(4):483-91. doi: 10.1007/s004250050347.

DOI:10.1007/s004250050347
PMID:9684353
Abstract

Post-embryonic development in plants is mainly achieved by its meristems. Within the Arabidopsis root meristem, both the fate and origin of its cells can be predicted with high accuracy. Mutants defective in the determination of root cell fates show that the corresponding genes are first required during embryogenesis. The sub-specification of cell fates, such as during epidermal root hair formation, involves transcription factors and phytohormones. In the Arabidopsis root, initial cell fate specification events must be followed by position-dependent reinforcement of cellular identity. A major question remains as to whether the signals that are involved in initiating the cellular pattern are the same or different from the signals used to reinforce it. The integrity of the root meristem is kept by balancing cell proliferation and cell differentiation, and differentiation-inhibiting signals originating from the quiescent centre are involved.

摘要

植物的胚后发育主要由其分生组织完成。在拟南芥根分生组织中,其细胞的命运和起源都能被高精度预测。在根细胞命运决定方面存在缺陷的突变体表明,相应基因在胚胎发育过程中是首先需要的。细胞命运的亚特异性,例如在表皮根毛形成过程中,涉及转录因子和植物激素。在拟南芥根中,初始细胞命运决定事件之后必须有细胞身份的位置依赖性强化。一个主要问题仍然存在,即启动细胞模式的信号与用于强化该模式的信号是相同还是不同。根分生组织的完整性通过平衡细胞增殖和细胞分化来维持,并且来自静止中心的分化抑制信号也参与其中。

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