Skottová N, Krecman V
Institute of Medical Chemistry, Medical Faculty, Palacký University, Olomouc, Czech Republic.
Acta Univ Palacki Olomuc Fac Med. 1998;141:39-40.
Silymarin administered to the rats concurrently with high cholesterol diet normalized the high cholesterol diet-induced retardation of disappearance of low density lipoproteins (LDL) from the medium during recirculating perfusion of livers from these rats. We suggest that the improvement of LDL removal by the liver after silymarin treatment contributes to the antihypercholesterolemic effect of silymarin.
在给大鼠喂食高胆固醇饮食的同时给予水飞蓟宾，可使高胆固醇饮食导致的这些大鼠肝脏在循环灌注期间低密度脂蛋白（LDL）从培养基中消失的延迟恢复正常。我们认为，水飞蓟宾治疗后肝脏对LDL清除的改善有助于水飞蓟宾的抗高胆固醇血症作用。
