Gupta S, Gupta M K, Gupta R, Mishra R S
Department of Pathology, Cancer Hospital and Research Institute, Gwalior, Madhya Pradesh, India.
Acta Cytol. 1998 Jul-Aug;42(4):959-62. doi: 10.1159/000331976.
Metastatic disease of the breast is often an unexpected diagnosis in a female presenting with a breast mass. The most common metastatic cancer to involve the breast is melanoma. Among gynecologic tumors, the most common primary is ovarian carcinoma. Carcinoma of the cervix metastasizing to the breast is extremely rare.
A 45-year-old female developed multiple bilateral breast masses during a course of radiotherapy for carcinoma of the cervix. Cytologic smears of the breast masses revealed adenocarcinomatous cells as well as keratinizing and nonkeratinizing malignant squamous cells, consistent with a histopathologic diagnosis of metastasizing adenosquamous carcinoma of the breast from primary cervical cancer.
Fine needle aspiration cytology diagnosis of malignancy metastatic to the breast is important to differentiate it from a second primary tumor and avoid an unnecessary mastectomy.