Kim T, Yoon G S, Kim O, Gong G
Department of Pathology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea.
Acta Cytol. 1998 Jul-Aug;42(4):1027-31. doi: 10.1159/000331953.
True malignant mixed tumor (carcinosarcoma), composed of carcinoma and sarcoma components, is rare in salivary gland neoplasms. Even rarer is a true malignant mixed tumor arising in the pleomorphic adenoma of the salivary gland.
A 64-year-old male was admitted with left pharyngeal pain. Head and neck magnetic resonance imaging revealed a left parapharyngeal mass; fine needle aspiration (FNA) cytology through the oral cavity was performed.
The aspirate presented a mixture of large, pleomorphic, vacuolated, single or multinucleated cells in a mucoid matrix and clusters of adenocarcinoma cells. Additionally, occasional benign glandular cells were noted. A cytologic diagnosis of malignant mixed tumor arising in the pleomorphic adenoma of the deep lobe of the parotid gland was made and confirmed by the surgically resected specimen.
真正的恶性混合瘤（癌肉瘤）由癌和肉瘤成分组成，在涎腺肿瘤中较为罕见。涎腺多形性腺瘤中发生的真正恶性混合瘤则更为罕见。
一名64岁男性因左侧咽痛入院。头颈部磁共振成像显示左侧咽旁肿块；通过口腔进行了细针穿刺（FNA）细胞学检查。
吸出物呈现出在黏液样基质中有大的、多形性的、空泡状的、单个或多核细胞以及腺癌细胞簇的混合物。此外，还发现了偶尔的良性腺细胞。做出了腮腺深叶多形性腺瘤中发生恶性混合瘤的细胞学诊断，并经手术切除标本证实。
