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高水果膳食摄入量后人体尿液中羟基肉桂酸酯和黄酮类化合物的检测

Urinary detection of hydroxycinnamates and flavonoids in humans after high dietary intake of fruit.

作者信息

Bourne L C, Rice-Evans C A

机构信息

International Antioxidant Research Centre, UMDS-Guy's Hospital Medical School, London, UK.

出版信息

Free Radic Res. 1998 Apr;28(4):429-38. doi: 10.3109/10715769809070812.

DOI:10.3109/10715769809070812
PMID:9684988
Abstract

The determination of the abilities of flavonoids, hydroxycinnamates and phenolics to scavenge free radicals in vitro suggests potent combined antioxidant activities of fruits, vegetables, beverages and grains. However, the key question of uptake in humans has only recently been approached consistently. The study described here demonstrates the uptake of hydroxycinnamates, for the first time, and other phenolic components, applying an HPLC method for their detection in the urine of subjects consuming levels of specific fruit equivalent to an approximate intake of 25 mg flavonol glycosides.

摘要

黄酮类化合物、羟基肉桂酸酯和酚类物质体外清除自由基能力的测定表明,水果、蔬菜、饮料和谷物具有强大的联合抗氧化活性。然而,人体吸收这一关键问题直到最近才得到持续关注。本文所述的研究首次证明了羟基肉桂酸酯以及其他酚类成分的吸收情况,该研究采用高效液相色谱法检测食用特定水果量(相当于约25毫克黄酮醇苷摄入量)的受试者尿液中的这些成分。

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