克雅氏病的新型变体形式。

The new variant form of Creutzfeldt-Jakob disease.

作者信息

Knight R, Stewart G

机构信息

National CJD Surveillance Unit, Western General Hospital, Edinburgh, UK.

出版信息

FEMS Immunol Med Microbiol. 1998 Jun;21(2):97-100. doi: 10.1111/j.1574-695X.1998.tb01154.x.

DOI:10.1111/j.1574-695X.1998.tb01154.x

PMID:9684998

Abstract

A new phenotype of Creutzfeldt-Jakob disease termed new variant Creutzfeldt-Jakob disease (nvCJD) was first described in March 1996. This differs from other forms of CJD in terms of its epidemiology, clinical features and neuropathology. To date 24 cases of this new form of CJD have been described, 23 within the UK. This article describes nvCJD discussing clinical and epidemiological features and discusses possible links with the bovine spongiform encephalopathy epidemic in cattle in the UK.

摘要

1996年3月首次描述了一种名为新型变异型克雅氏病（nvCJD）的克雅氏病新表型。这种疾病在流行病学、临床特征和神经病理学方面与其他形式的克雅氏病不同。迄今为止，已报道了24例这种新型克雅氏病病例，其中23例在英国。本文描述了新型变异型克雅氏病，讨论了其临床和流行病学特征，并探讨了与英国牛群中牛海绵状脑病疫情的可能联系。