荧光原位杂交技术的进展
Advances in fluorescence in situ hybridization.
作者信息
Raap A K
机构信息
Laboratory for Cytochemistry and Cytometry, Department of Molecular Cell Biology, Leiden University Medical Center, Wassenaarseweg 72, 2333 AL Leiden, Netherlands.
出版信息
Mutat Res. 1998 May 25;400(1-2):287-98. doi: 10.1016/s0027-5107(98)00029-3.
The techniques of in situ hybridization (ISH) are widely applied for analyzing the genetic make-up and RNA expression patterns of individual cells. This review focusses on a number of advances made over the last 5 years in the fluorescence ISH (FISH) field, i.e., Fiber-FISH, Multi-colour chromosome painting, Comparative Genomic Hybridization, Tyramide Signal Amplification and FISH with Polypeptide Nucleic Acid and Padlock probes.
原位杂交（ISH）技术被广泛应用于分析单个细胞的基因组成和RNA表达模式。本综述聚焦于荧光原位杂交（FISH）领域在过去5年取得的一些进展，即纤维荧光原位杂交（Fiber-FISH）、多色染色体描绘、比较基因组杂交、酪胺信号放大以及使用多肽核酸和锁式探针的荧光原位杂交。
Zotero 插件