Futai M, Oka T, Moriyama Y, Wada Y
Division of Biological Sciences, Institute of Scientific and Industrial Research, Osaka University, Ibaraki, Osaka, 567-0047, Japan.
J Biochem. 1998 Aug;124(2):259-67. doi: 10.1093/oxfordjournals.jbchem.a022105.
Eukaryotic cells have developed an array of endomembrane systems that have differentiated to carry out various functions. They are involved in the pathways of endocytosis and exocytosis, and have an acidic lumenal pH ranging from 4.5 to 6.5. This review describes recent studies on the animal cell organelles and how they relate to the well studied systems of yeast. We focus mainly on (i) the primary proton pump (vacuolar type H+-ATPase) and other factors that establish acidic pH, and (ii) functions of the organelles as related to lumenal acidity.
真核细胞已经发展出一系列分化以执行各种功能的内膜系统。它们参与内吞作用和外排作用途径，并且具有4.5至6.5的酸性内腔pH值。本综述描述了关于动物细胞细胞器的最新研究以及它们与已充分研究的酵母系统的关系。我们主要关注：（i）主要质子泵（液泡型H + -ATP酶）和其他建立酸性pH值的因素，以及（ii）与内腔酸度相关的细胞器功能。
