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[1995年古巴柯萨奇病毒B5型脑膜脑炎暴发]

[Outbreak of Coxsackievirus B5 meningoencephalitis in Cuba, 1995].

作者信息

Bello M, Más Lago P, Palomera R, González Z

机构信息

Instituto de Medicina Tropical Pedro Kourí.

出版信息

Rev Cubana Med Trop. 1997;49(1):69-70.

PMID:9685965
Abstract

An increase in the reported cases of viral meningoencephalitis (VME) was detected in October and November, 1995, compared with the same period of 1994. 43 stock specimens from children with this diagnosis were received at the Laboratory of Enterovirus from the "Pedro Kourí" Institute of Tropical Medicine. 23 isolations (53.4%) were obtained and identified as Coxsackievirus B5. Besides, in 43 matched sera investigated by the neutralization test against some Enteroviruses, 21 proved to be positive (48.8%) to the isolated agent. This allowed us to affirm, supported by the clinical picture and by epidemiology, that we are in the presence of an VME outbreak produced by Coxsackievirus B5.

摘要

与1994年同期相比,1995年10月和11月报告的病毒性脑膜脑炎(VME)病例有所增加。“佩德罗·库里”热带医学研究所肠道病毒实验室收到了43份诊断为此病的儿童库存标本。获得了23次分离培养物(53.4%),并鉴定为柯萨奇病毒B5型。此外,在对一些肠道病毒进行中和试验检测的43份配对血清中,21份对分离出的病原体呈阳性反应(48.8%)。这使我们能够在临床症状和流行病学的支持下确认,我们正面临由柯萨奇病毒B5型引起的VME疫情。

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