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[Monoclonal antibodies which recognize herpes simplex virus and their possible diagnostic application].

作者信息

Pupo Antúnez M, Hermida Díaz C, Morier Díaz L, García Infante S, Resik Aguirre S

机构信息

Instituto de Medicina Tropical Pedro Kourí, Ciudad de La Habana, Cuba.

出版信息

Rev Cubana Med Trop. 1997;49(3):181-5.

PMID:9685985
Abstract

It is reported the obtention of monoclonal antibodies, which are capable of recognizing HSV-1 and HSV-2 viruses, by the conventional technology of cellular fusion. The monoclonal antibodies of highest positivity according to the indirect immunofluorescence technique were partially characterized. It was determined the neutralizing capacity of 2 of them (278-F7 and 70-G10), which were used to identify isolations of clinical specimens by indirect immunofluorescence. These monoclonal antibodies recognized HSV-1 up to a dilution of 1:2 560.

摘要

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