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[雾化吸入疗法在耳鼻咽喉科的应用。文献综述]

[Nebulization aerosol therapy in otorhinolaryngology. Review of the literature].

作者信息

Bonfils P

机构信息

Service d'ORL et de Chirurgie Cervico-Faciale, Hôpital Boucicaut, Faculté Necker-Enfants Malades, Université Paris V.

出版信息

Ann Otolaryngol Chir Cervicofac. 1997;114(5):147-56.

PMID:9686025
Abstract

An aerosol is a suspension of solid or liquid particles in a gas with a negligable rate of fall. Administration with a nebulizer is an administration route just as are the oral, intramuscular or intravenous routes. Nebulization should not be considered as a simple, somewhat mysterious, adjunct, but rather as an effective administration route of active drugs. Drug administration by nebulization is widespread in France, being prescribed by general practitioners and ENT specialists. The main indications involve lund or ENT diseases. In general practice, there are four main indications including two for which there is no convincing evidence of its efficacy (acute and chronic sinusitis) and two for which pneumologists disagree on the "indications" (acute and chronic bronchitis). The aim of this review is to analyse the literature on this administration route for cervicofacial indications and discuss the different drugs used. Current practice will be assessed.

摘要

气雾剂是固体或液体颗粒在气体中的悬浮液,其沉降速率可忽略不计。使用雾化器给药是一种给药途径,与口服、肌肉注射或静脉注射途径一样。雾化不应被视为一种简单、有点神秘的辅助手段,而应被视为活性药物的一种有效给药途径。雾化给药在法国广泛应用,由全科医生和耳鼻喉科专家开出处方。主要适应症涉及肺部或耳鼻喉疾病。在一般实践中,有四个主要适应症,其中两个没有令人信服的疗效证据(急性和慢性鼻窦炎),另外两个呼吸科医生在“适应症”上存在分歧(急性和慢性支气管炎)。本综述的目的是分析关于这种给药途径用于颌面适应症的文献,并讨论所使用的不同药物。将评估当前的实践情况。

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