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[曲安奈德六醋酸酯椎间盘内注射并发症的神经外科治疗。放射学-临床分类的价值]

[Neurosurgical treatment of complications of intra-disk injections of triamcinolone hexacetonide. Value of a radio-clinical classification].

作者信息

Privat J M, Finiels P J

机构信息

Service de Neurochirurgie A, Centre Médico-Chirurgical Gui-de-Chauliac, Montpellier.

出版信息

Neurochirurgie. 1997;43(4):212-9.

PMID:9686223
Abstract

Epidural granulomas following intra-discal injection of triamcinolone hexacetonide are a well-known complication of this procedure, which is still encountered, even if its utilization was discontinued several years ago. According to the results of their experience, the authors propose a new radio-clinical grading system: grade I: disc calcification with aspect of "sub-ligamentar hernia" on CT scan; grade II: ascendant or descendant retrosomatic migration of distal content; grade III: pseudotumoral epidural infiltrate producing progressive narrowing of the spinal canal with neurological disturbance. Surgical indications in these cases can be drawn from their evolution: posterior approach can be used, with or without laminectomy, for excision as complete as possible of the involved disc (grades I and II); anterior approach should be preferred in cases of multiples recurrences after medical treatment and failure of classical posterior approach, or in case of necrotico-inflammatory proliferation with narrowing of the spinal canal (grade III).

摘要

椎间盘内注射己曲安奈德后发生的硬膜外肉芽肿是该操作的一种已知并发症,即使其使用在数年前已停止,现在仍会遇到。根据他们的经验结果,作者提出了一种新的放射学 - 临床分级系统:I级:CT扫描显示椎间盘钙化且有“韧带下疝”表现;II级:远端内容物向上或向下的后躯体迁移;III级:假性肿瘤性硬膜外浸润导致椎管逐渐狭窄并伴有神经功能障碍。这些病例的手术指征可根据其病情发展确定:对于I级和II级病例,可采用后路手术,可进行或不进行椎板切除术,以尽可能完整地切除受累椎间盘;对于经药物治疗多次复发且经典后路手术失败的病例,或出现坏死性炎症增殖并伴有椎管狭窄的病例(III级),应首选前路手术。

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