Koçak I, Yalvaç I S, Koçak A, Nurözler A, Unlü N, Kasim R, Duman S
Department of Ophthalmology, Ankara Hospital, Turkey.
Acta Ophthalmol Scand. 1998 Jun;76(3):343-5. doi: 10.1034/j.1600-0420.1998.760318.x.
A clinical double-blind study was performed in patients who had undergone extracapsular cataract extraction and intraocular lens implantation (ECCE+IOL) to compare the anti-inflammatory effects of diclofenac sodium 0.1% and flurbiprofen 0.03% eye drops.
The diclofenac group included 21 eyes of 21 patients and the flurbiprofen group included 22 eyes of 22 patients. The parameters compared were pachymetry of the cornea, corneal surface changes, intraocular pressure (IOP) and the degree of inflammation of the anterior chamber at one, three and six weeks after cataract surgery.
There was no statistically significant difference between the two treatment groups in corneal pachymetry, corneal surface changes, IOP and the anterior chamber inflammation (p>0.05).
Both drugs were well tolerated and may be safely used to reduce inflammation for cataract surgery.
对接受了白内障囊外摘除术和人工晶状体植入术（ECCE+IOL）的患者进行了一项临床双盲研究，以比较0.1%双氯芬酸钠滴眼液和0.03%氟比洛芬滴眼液的抗炎效果。
双氯芬酸组包括21例患者的21只眼，氟比洛芬组包括22例患者的22只眼。比较的参数包括白内障手术后1周、3周和6周时的角膜厚度测量、角膜表面变化、眼压（IOP）和前房炎症程度。
两个治疗组在角膜厚度测量、角膜表面变化、眼压和前房炎症方面无统计学显著差异（p>0.05）。
两种药物耐受性良好，可安全用于减轻白内障手术的炎症。
