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[动脉粥样硬化中颈动脉分叉的多模态研究方法]

[Multimodal approach to carotid bifurcation in atherosclerosis].

作者信息

Rolland Y, Sirop V, Lucas A, Rambeau M, Morcet N, Duvauferrier R

机构信息

Département de Radiologie et d'Imagerie Médicale, Hôpital Sud, Rennes.

出版信息

Ann Radiol (Paris). 1996;39(6):221-33.

PMID:9687616
Abstract

The cost of treatment of ischemic stroke (second cause of death for elderly patients) is increasing. carotid bifurcation surgery can change the prognosis (as proven by NASCET and ECST studies) for symptomatic patients with over 70% of carotid narrowing. Exploration of the carotid bifurcation is an important step in the diagnosis and must assess the degree of stenosis, the smoothness of the plaque and describe the collateral vessels. Duplex sonography is used to analyze the plaque and to measure the hemodynamic consequences beyond the stenosis. Transcranial Doppler is used to study the hemodynamic consequences at the circle of Willis. 3D TOF MR Angiography visualizes vessels using MIP but with a risk of overestimation of the degree of stenosis. A good morphological study of the circle of Willis can be achieved. With spiral CT, 3D data bases can be acquired with a single injection of contrast medium. Analysis is based on native, reformatted and MIP images. The image quality is generally good, but decreases in the case of huge calcifications. Brain examination can be performed in the same session, looking for rupture of the blood-brain barrier. Angiography remains the gold standard with a high complication rate. It allows excellent analysis from the aortic arch to distal cortical vessels. Isotope studies are only performed in difficult cases (vertebro-basilar lesions, differential diagnosis). Duplex ultrasound is performed first in all protocols. Until recently, angiography was performed before surgery, but the current tendency is to use a less invasive examination (MR angiography or CT angiography) and angiography is then only performed when necessary. A knowledge of the respective advantages of each technique is essential in order to adapt the protocols to each local team.

摘要

缺血性中风(老年患者的第二大致死原因)的治疗成本正在增加。颈动脉分叉手术可以改变有症状且颈动脉狭窄超过70%患者的预后(如北美症状性颈动脉内膜切除术试验和欧洲颈动脉外科试验研究证实)。颈动脉分叉探查是诊断中的重要一步,必须评估狭窄程度、斑块的光滑度并描述侧支血管。双功超声用于分析斑块并测量狭窄远端的血流动力学影响。经颅多普勒用于研究 Willis 环处的血流动力学影响。三维时间飞跃磁共振血管造影使用最大密度投影法使血管显影,但存在高估狭窄程度的风险。可以对 Willis 环进行良好的形态学研究。使用螺旋CT,单次注射造影剂即可获取三维数据库。分析基于原始图像、重组图像和最大密度投影图像。图像质量一般较好,但在巨大钙化的情况下会下降。可以在同一次检查中进行脑部检查,寻找血脑屏障的破裂情况。血管造影仍然是金标准,但并发症发生率较高。它可以对从主动脉弓到远端皮质血管进行出色的分析。同位素研究仅在疑难病例(椎基底病变、鉴别诊断)中进行。在所有检查方案中,首先进行双功超声检查。直到最近,血管造影还是在手术前进行,但目前的趋势是使用侵入性较小的检查(磁共振血管造影或CT血管造影),然后仅在必要时进行血管造影。了解每种技术的各自优势对于使检查方案适应每个当地团队至关重要。

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