Babetty Z, Sümer A, Altintaş S, Ergüney S, Göksel S
Biomedical Engineering Institute, Bogaziçi University, Istanbul, Turkey.
Arch Surg. 1998 Jul;133(7):727-34. doi: 10.1001/archsurg.133.7.727.
To evaluate and compare the in vivo strength, knot efficiency, and knot security of 4 types of sliding knots, and to assess tissue reaction to study the effect of knot configuration, knot volume, and suture size.
Randomized trial.
Experimental Medical Research Institute, Istanbul, Turkey.
Wistar rats.
To assess the tissue reaction, a midline laparotomy incision was made in 112 rats and sutured with various interrupted knots in silk and nylon sutures of 2/0 and 4/0 (United States Pharmacopeia) sizes. Suture loops were implanted in subcutaneous pouches in the rat abdomen. Sutures were all extracted at days 4, 7, 11, and 20 to determine their knot-holding capacity.
Knot efficiency and percentage decrease in knot-holding capacity were examined. Knot, tissue reaction, and inflammatory sheath volumes were measured.
The 4/0 knots lost more strength than the 2/0 knots. The alternating knots with different patterns were more efficient and secure than the simple alternating ones. The alternating parallel knot was found to be unreliable. The tissue response to all the knots, except 2/0 nylon, was similar. The inflammatory sheath volume varied depending on the knot volume, suture size, and knot configuration.
The use of alternating sliding knots with different patterns is recommended to replace simple alternating sliding knots.
评估并比较4种类型滑结的体内强度、结效率和结安全性，并评估组织反应以研究结构型、结体积和缝线尺寸的影响。
随机试验。
土耳其伊斯坦布尔实验医学研究所。
Wistar大鼠。
为评估组织反应，在112只大鼠身上做中线剖腹切口，并用2/0和4/0（美国药典规格）的丝线和尼龙缝线以各种间断结进行缝合。将缝线环植入大鼠腹部的皮下袋中。在第4、7、11和20天取出所有缝线以确定其结保持能力。
检查结效率和结保持能力的百分比下降情况。测量结、组织反应和炎性鞘体积。
4/0结比2/0结失去的强度更多。不同模式的交替结比简单交替结更有效且更安全。发现交替平行结不可靠。除2/0尼龙线外，所有结的组织反应相似。炎性鞘体积因结体积、缝线尺寸和结构型而异。
建议使用不同模式的交替滑结来替代简单交替滑结。
