Cassidy W
Louisiana State University Medical Center, Baton Rouge, USA.
Pediatr Infect Dis J. 1998 Jul;17(7 Suppl):S43-6. doi: 10.1097/00006454-199807001-00006.
To increase hepatitis B vaccination coverage of adolescents, a public/private partnership was organized in the greater Baton Rouge area of Louisiana in 1992 to fund and implement school-based vaccination programs.
Initial programs utilized schools with existing school-based clinics and administered 2 to 3 doses of hepatitis B vaccine to up to 76% of eligible students. During 1996 to 1997, expansion from 4 schools to 68 schools was facilitated by the use of temporary clinics set up in open school space. This multifaceted program administered 3 doses of hepatitis B vaccine to 3232 students (75%) and 2 doses to 171 students (4%). Administration of the 3-dose regimen of hepatitis B vaccine was aided by the use of a dosing schedule at 0, 2 and 4 months. This accelerated dosing has been shown to provide seroprotection for greater than 95% of healthy adolescents.
In the Baton Rouge area, the hepatitis B adolescent vaccination program has immunized approximately 5000 adolescents during a 5-year period with minimal use of financial and personnel resources.
The success and growth of this program demonstrate that school-based vaccination programs can be highly efficient and effective.
为提高青少年乙肝疫苗接种率，1992年在路易斯安那州大巴吞鲁日地区组织了一项公私合作项目，为基于学校的疫苗接种计划提供资金并予以实施。
最初的项目利用现有的校内诊所，为多达76%符合条件的学生接种2至3剂乙肝疫苗。在1996年至1997年期间，通过在学校开放空间设立临时诊所，实现了从4所学校扩展至68所学校。这个多方面的项目为3232名学生（75%）接种了3剂乙肝疫苗，为171名学生（4%）接种了2剂。使用0、2和4个月的接种时间表辅助实施3剂次乙肝疫苗接种方案。这种加速接种已被证明能为超过95%的健康青少年提供血清保护。
在巴吞鲁日地区，乙肝青少年疫苗接种项目在5年期间用极少的财政和人力资源为大约5000名青少年进行了免疫接种。
该项目的成功与发展表明，基于学校的疫苗接种计划可以非常高效。
