Figueroa-Colon R, Mayo M S, Treuth M S, Aldridge R A, Weinsier R L
Department of Pediatrics, Children's Hospital, University of Alabama at Birmingham, 35233, USA.
Obes Res. 1998 Jul;6(4):262-7. doi: 10.1002/j.1550-8528.1998.tb00348.x.
Regulation of growth and development, clinical assessment, and obesity are among the areas of nutrition-related research, wherein accurate assessment of body composition is important. We want to test the hypothesis that dual-energy X-ray absorptiometry (DXA) measurements are reproducible in healthy girls.
We determined total body composition measurements in healthy prepubertal girls using DXA twice, 6 weeks apart.
We studied 61 healthy, normal-weight, prepubertal girls, aged 4.8 years to 10.3 years. The girls' DXA-derived mean weight between visits 1 and 2 significantly increased (27.14 kg vs. 27.80 kg, p<0.0001). The increased weight was due to significant increases in total body fat-free mass (FFM) (19.53 kg vs. 19.89 kg, p<0.001), total body bone mass (1.05 kg vs. 1.07 kg, p<0.0001), and total body fat mass (7.61 kg vs. 7.91 kg, p<0.03). The girls' DXA-derived mean total trunk mass between visits 1 and 2 significantly increased ( 11.23 kg vs. 11.63 kg, p<0.0001), as did total leg mass (9.33 kg vs. 9.53 kg, p<0.00), although no significant differences were observed in total arm mass (2.52 kg vs. 2.54 kg, p=0.37). The Pearson coefficient of correlation (r) and total coefficient of variation (CV) for intraindividual measurements by DXA were: weight--r=0.99, CV = 1.97%; total body FFM--r = 0.96, CV = 2.30%; total body bone mass--r = 0.99, CV=2.08%; total body fat mass--r=0.96, CV=6.55%; percentage total body fat--r=0.91, CV=5.69%; total trunk mass--r=0.96, CV= 3.59%; total arm mass--r= 0.95, CV =4.09%; and total leg mass--r = 0.99, CV = 2.75%.
Total body FFM, total body bone mass, total body fat mass, percentage of total body fat mass, as well as regional mass determinations by DXA, were highly reproducible in healthy, normal-weight, prepubertal girls. We highly recommend the use of DXA for total body composition studies in girls aged 5 years to 10 years.
生长发育调节、临床评估和肥胖是营养相关研究的领域，其中准确评估身体成分很重要。我们想要检验双能X线吸收法（DXA）测量在健康女孩中具有可重复性这一假设。
我们使用DXA对健康的青春期前女孩进行全身成分测量，两次测量间隔6周。
我们研究了61名健康、体重正常的青春期前女孩，年龄在4.8岁至10.3岁之间。第1次和第2次测量之间女孩通过DXA得出的平均体重显著增加（27.14千克对27.80千克，p<0.0001）。体重增加是由于全身去脂体重（FFM）显著增加（19.53千克对19.89千克，p<0.001）、全身骨量（1.05千克对1.07千克，p<0.0001）和全身脂肪量（7.61千克对7.91千克，p<0.03）。第1次和第2次测量之间女孩通过DXA得出的平均总躯干质量显著增加（11.23千克对11.63千克，p<0.0001），总腿部质量也是如此（9.33千克对9.53千克，p<0.00），不过总手臂质量未观察到显著差异（2.52千克对2.54千克，p = 0.37）。DXA进行个体内测量的皮尔逊相关系数（r）和总变异系数（CV）分别为：体重——r = 0.99，CV = 1.97%；全身FFM——r = 0.96，CV = 2.30%；全身骨量——r = 0.99，CV = 2.08%；全身脂肪量——r = 0.96，CV = 6.55%；全身脂肪百分比——r = 0.91，CV = 5.69%；总躯干质量——r = 0.96，CV = 3.59%；总手臂质量——r = 0.95，CV = 4.09%；总腿部质量——r = 0.99，CV = 2.75%。
在健康、体重正常的青春期前女孩中，全身FFM、全身骨量、全身脂肪量、全身脂肪量百分比以及通过DXA进行的局部质量测定具有高度可重复性。我们强烈建议在5岁至10岁女孩的全身成分研究中使用DXA。
